CREBBP Rabbit Polyclonal Antibody — image 1 of 3

Product details

CREBBP Rabbit Polyclonal Antibody

Catalog number HA500056

Price for HA500056

Size / count 100 µL

About this product

Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like DDX21, FBL, IRF2, MAFG, NCOA3, POLR1E/PAF53 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER). Acetylates POLR1E/PAF53, leading to decreased association of RNA polymerase I with the rDNA promoter region and coding region . Acetylates DDX21, thereby inhibiting DDX21 helicase activity. Acetylates FBL, preventing methylation of 'Gln-105' of histone H2A (H2AQ104me). Functions as a transcriptional coactivator for SMAD4 in the TGF-beta signaling pathway.

Specifications

Catalog number: HA500056
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CBP antibody CBP_HUMAN antibody CREB binding protein antibody CREB-binding protein antibody Crebbp antibody Cyclic AMP responsive enhancer binding protein antibody KAT3A antibody RSTS antibody RTS antibody Rubinstein Taybi syndrome antibody
Abbreviation: CREBBP CBP
Swiss Prot: Q92793 Human, P45481 Mouse
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within C-terminal human CREBBP.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: Human lung carcinoma tissue, mouse cerebellum tissue, rat bladder tissue, rat colon tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:500-1:1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size:265 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CREBBP Rabbit Polyclonal Antibody?

The catalog number for CREBBP Rabbit Polyclonal Antibody is HA500056.

What sizes are available for CREBBP Rabbit Polyclonal Antibody?

CREBBP Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CREBBP Rabbit Polyclonal Antibody in stock?

CREBBP Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CREBBP Rabbit Polyclonal Antibody used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.