Nucleoside Phosphorylase Rabbit Polyclonal Antibody

About this product

Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes inosine into hypoxanthine and guanosine into guanine, in each case creating ribose phosphate. Note: adenosine is first metabolized to inosine via the enzyme adenosine deaminase.One of the reaction catalyzed by purine nucleoside phosphorylase in purine metabolism.Nucleoside phosphorylase is an enzyme which cleaves a nucleoside by phosphorylating the ribose to produce a nucleobase and ribose 1 phosphate. It is one enzyme of the nucleotide salvage pathways. These pathways allow the cell to produce nucleotide monophosphates when the de novo synthesis pathway has been interrupted or is non-existent (as is the case in the brain). Often the de novo pathway is interrupted as a result of chemotherapy drugs such as methotrexate or aminopterin.All salvage pathway enzymes require a high energy phosphate donor such as ATP or PRPP.

Specifications

Catalog number

HA500062

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

FLJ94043 antibody FLJ97288 antibody FLJ97312 antibody Inosine phosphorylase antibody Inosine-guanosine phosphorylase antibody MGC117396 antibody MGC125915 antibody MGC125916 antibody NP antibody Np1 antibody Nucleoside phosphorylase antibody PNP antibody Pnp1 antibody PNPH_HUMAN antibody PRO1837 antibody PUNP antibody Purine nucleoside orthophosphate ribosyltransferase antibody Purine nucleoside phosphorylase 5a antibody Purine nucleoside phosphorylase antibody

Abbreviation

Purine nucleoside phosphorylase PNP Inosine phosphorylase Inosine-guanosine phosphorylase

Swiss Prot

P00491 Human, P85973 Rat

Cellular Locus

Cytoplasm, Cytoskeleton.

Host

Rabbit

Species Reactivity

Human, Rat

Immunogen

Recombinant protein within human Nucleoside Phosphorylase aa 1-200.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Rat spleenl tissue lysate, Jurkat cell lysate, K562 cell lysate, human placenta tissue, human small intestine tissue, SiHa.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:200-1:1,000;FC: 1:500-1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

32 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No