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Product details

GABRB3 Rabbit Polyclonal Antibody

Catalog number HA500090

Price for HA500090

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Size / count 100 µL

About this product

Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel. The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta3/gamma2 receptor exhibits synaptogenic activity. The alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity. Functions also as histamine receptor and mediates cellular responses to histamine. Plays an important role in somatosensation and in the production of antinociception.

Specifications

Catalog number
HA500090
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
ECA5 antibody GABA alpha receptor beta-2 subunit antibody GABA (A) receptor subunit beta-3 antibody GABAA receptor beta 3 subunit antibody GABAA receptor subunit beta 3 antibody GABR B3 antibody Gabrb3 antibody Gamma aminobutyric acid (GABA) A receptor beta 3 antibody Gamma aminobutyric acid receptor subunit beta 3 antibody Gamma-aminobutyric acid receptor subunit beta-3 antibody GBRB3_HUMAN antibody MGC9051 antibody
Abbreviation
Gamma-aminobutyric acid receptor subunit beta-3, GABA (A) receptor subunit beta-3, GABAAR subunit beta-3, GABRB3
Swiss Prot
P28472 Human, P63080 Mouse, P63079 Rat
Cellular Locus
Plasma membrane, Cell membrane, Cytoplasmic vesicle membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human GABRB3 aa 400-443 (Cytoplasmic domain).
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Rat brain tissue lysate, rat cerebellum tissue lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, HepG2 cell lysate, 293 cell lysate, rat brain tissue, human lung tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 54 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for GABRB3 Rabbit Polyclonal Antibody?

The catalog number for GABRB3 Rabbit Polyclonal Antibody is HA500090.

What sizes are available for GABRB3 Rabbit Polyclonal Antibody?

GABRB3 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is GABRB3 Rabbit Polyclonal Antibody in stock?

GABRB3 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is GABRB3 Rabbit Polyclonal Antibody used for?

Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion chan

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

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