AMPS Rabbit Polyclonal Antibody

About this product

Adenylosuccinate lyase (ASL) is an enzyme that catalyzes two reactions in the de novo purine biosynthetic pathway. In both reactions it uses an E1cb elimination reaction mechanism to cleave fumarate off of the substrate. In the first reaction, ASL converts 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR) to 5-aminoimidazole-4-carboxamide ribotide (AICAR) and fumarate. AICAR proceeds through three more reactions before it becomes adenylosuccinate (also called succinyladenosine monophosphate or SAMP), which ASL then splits into adenosine monophosphate (AMP) and fumarate. ASL is important to cells not only because of its involvement in creating purines needed for cellular replication, but also because it helps regulate metabolic processes by controlling the levels of AMP and fumarate in the cell.

Specifications

Catalog number

HA500092

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Adenylosuccinase antibody Adenylosuccinate lyase antibody ADSL antibody AMPS antibody ASase antibody ASL antibody OTTHUMP00000199172 antibody OTTHUMP00000199173 antibody PUR8_HUMAN antibody

Abbreviation

Adenylosuccinate lyase1 Publication ADSL1 Publication ASL Adenylosuccinase1 Publication ASase

Swiss Prot

P30566 Human, P54822 Mouse

Cellular Locus

Cytosol.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within N-terminal human AMPS.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

Jurkatcell lysate, NIH/3T3 cell lysate, mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

54 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No