ATG14L Rabbit Polyclonal Antibody — image 1 of 3

Product details

ATG14L Rabbit Polyclonal Antibody

Catalog number HA500096

Price for HA500096

Size / count 100 µL

About this product

Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1. Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK. Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion. Modulates the hepatic lipid metabolism (By similarity).

Specifications

Catalog number: HA500096
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 4832427M01 antibody ATG14 antibody Atg14L antibody Autophagy-related protein 14-like protein antibody BAKOR_HUMAN antibody Barkor antibody Beclin 1-associated autophagy-related key regulator antibody D14Ertd114e antibody D14Ertd436e antibody KIAA0831 antibody mCG_6911 antibody
Abbreviation: ATG14
Swiss Prot: Q6ZNE5 Human, Q8CDJ3 Mouse, D4A4K3 Rat
Cellular Locus: Endoplasmic reticulum membrane, Cytoplasm, Preautophagosomal structure membrane, autophagosome membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human ATG14L aa 421-456.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: Hela cell lysate, MCF-7 cell lysate, HepG2 cell lysate, SiHa cell lysate, rat brain tissue, human colon tissue, mouse testis tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 55 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for ATG14L Rabbit Polyclonal Antibody?

The catalog number for ATG14L Rabbit Polyclonal Antibody is HA500096.

What sizes are available for ATG14L Rabbit Polyclonal Antibody?

ATG14L Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is ATG14L Rabbit Polyclonal Antibody in stock?

ATG14L Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is ATG14L Rabbit Polyclonal Antibody used for?

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.