Product details
Catalog number HA500098
Price for HA500098
Size / count 100 µL
Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
The catalog number for GPR161 Rabbit Polyclonal Antibody is HA500098.
GPR161 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.
GPR161 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.
Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, lead
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