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Product details

GPR161 Rabbit Polyclonal Antibody

Catalog number HA500098

Price for HA500098

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Size / count 100 µL

About this product

Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

Specifications

Catalog number
HA500098
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
G protein coupled receptor 161 antibody G protein coupled receptor RE2 antibody RE2 antibody Gm208 G-protein coupled receptor 161
Abbreviation
GPR161
Swiss Prot
B2RPY5 Mouse
Cellular Locus
Cilium membrane, Cell membrane.
Host
Rabbit
Species Reactivity
Mouse, Rat
Immunogen
Recombinant protein within mouse GPR161 aa 323-545.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Mouse cerebellum tissue lysate, rat colon tissue lysate, rat uterus tissue, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
60 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for GPR161 Rabbit Polyclonal Antibody?

The catalog number for GPR161 Rabbit Polyclonal Antibody is HA500098.

What sizes are available for GPR161 Rabbit Polyclonal Antibody?

GPR161 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is GPR161 Rabbit Polyclonal Antibody in stock?

GPR161 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is GPR161 Rabbit Polyclonal Antibody used for?

Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, lead

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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