CD66b Rabbit Polyclonal Antibody — image 1 of 3

Product details

CD66b Rabbit Polyclonal Antibody

Catalog number HA500100

Price for HA500100

Size / count 100 µL

About this product

Carcinoembryonic antigen-related cell adhesion molecule 8, also designated CD67, CD66b or nonspecific cross-reacting antigen (NCA-95), belongs to the human carcinoembryonic antigen (CEA) family. The CD67 antigen is encoded by the CEACAM8 (CGM6) gene, which is exclusively expressed in neutrophils and eosinophils. In neutrophils, the CEACAM8 gene is primarily detected in the secondary granules within the cytoplasm, but it can also be found in lower amounts on the plasma membrane. The amount of CD67 on the plasma membrane is up-regulated upon granulocyte activation. CD67 has been located on the surface of neutrophilic and eosinophilic granulocytes at late stages of differentiation. It exhibits heterophilic cell adhesion properties with CD66c, which is coexpressed with CD67 in granulocytes. CD67, which is attached to the membrane by a GPI-anchor, is expressed in leukocytes of chronic myeloid leukemia patients and bone marrow and in granulocytes in the spleen, thymus and lungs.

Specifications

Catalog number: HA500100
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Carcinoembryonic antigen CGM6 antibody Carcinoembryonic antigen gene family member 6 antibody Carcinoembryonic antigen related cell adhesion molecule 8 antibody Carcinoembryonic antigen-related cell adhesion molecule 8 antibody CD 66b antibody CD 67 antibody CD66b antibody CD66b antigen antibody CD67 antibody CD67 antigen antibody CEACAM 8 antibody CEACAM8 antibody CEAM8_HUMAN antibody CGM 6 antibody CGM6 antibody NCA 95 antibody NCA95 antibody Non-specific cross-reacting antigen NCA-95 antibody Nonspecific cross reacting antigen NCA 95 antibody Nonspecific cross reacting antigen NCA95 antibody
Abbreviation: CEACAM8
Swiss Prot: P31997 Human
Cellular Locus: Cell membrane, Cell surface.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human CD66b aa 1-250.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, mIHC, IF-Tissue
Positive Control: Human cervical cancer, human colon cancer tissue, human breast cancer tissue, human spleen tissue, human colon tissue, U937 cell lysate, A431 cell lysate, Daudi cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:1,000 ;mIHC: 1:1,000 ;IF-Tissue: 1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 38 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CD66b Rabbit Polyclonal Antibody?

The catalog number for CD66b Rabbit Polyclonal Antibody is HA500100.

What sizes are available for CD66b Rabbit Polyclonal Antibody?

CD66b Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CD66b Rabbit Polyclonal Antibody in stock?

CD66b Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD66b Rabbit Polyclonal Antibody used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.