Gemin 2 Rabbit Polyclonal Antibody

Catalog number HA500106

Price for HA500106

Size / count 100 µL

About this product

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Specifications

Catalog number: HA500106
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Component of gems 2 antibody Gem (nuclear organelle) associated protein 2 antibody Gem associated protein 2 antibody GEMI2_HUMAN antibody Gemin-2 antibody gemin2 antibody SIP 1 antibody SIP-1 antibody SIP1 antibody SIP1 delta antibody SIP1-delta antibody SMN interacting protein 1 antibody SMN interacting protein 1 delta antibody SMN-interacting protein 1 antibody Survival interacting protein 1 antibody Survival of motor neuron protein interacting protein 1 antibody Survival of motor neuron protein-interacting protein 1 antibody
Abbreviation: Gem-associated protein 2 Gemin-2 Component of gems 2 Survival of motor neuron protein-interacting protein 1 SMN-interacting protein 1
Swiss Prot: O14893 Human
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within human Gemin 2 aa 10-60.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB
Positive Control: 293 cell lysate, MCF-7 cell lysate, K562 cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 32 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Gemin 2 Rabbit Polyclonal Antibody?

The catalog number for Gemin 2 Rabbit Polyclonal Antibody is HA500106.

What sizes are available for Gemin 2 Rabbit Polyclonal Antibody?

Gemin 2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Gemin 2 Rabbit Polyclonal Antibody in stock?

Gemin 2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Gemin 2 Rabbit Polyclonal Antibody used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.