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Product details

PP1C gamma Rabbit Polyclonal Antibody

Catalog number HA500138

Price for HA500138

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Size / count 100 µL

About this product

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective.

Specifications

Catalog number
HA500138
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
PP 1G antibody PP-1G antibody PP1C antibody PP1G antibody PP1G_HUMAN antibody PP1gamma antibody PPP 1G antibody PPP1CC antibody PPP1G antibody Protein phosphatase 1, catalytic subunit, gamma isozyme antibody Protein phosphatase 1C catalytic subunit antibody Serine/threonine phosphatase 1 gamma antibody Serine/threonine protein phosphatase PP1 gamma catalytic subunit antibody Serine/threonine-protein phosphatase PP1-gamma catalytic subunit antibody
Abbreviation
PPP1CC
Swiss Prot
P36873 Human, P63087 Mouse, P63088 Rat
Cellular Locus
Nucleus, Mitochondrion, Cytoplasm, Kinetochore, Cleavage furrow, Midbody.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human PP1C gamma aa 293-323.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
293 cell lysate, mouse lung tissue lysate, rat brain tissue lysate, human prostate tissue, human stomach tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000 ;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for PP1C gamma Rabbit Polyclonal Antibody?

The catalog number for PP1C gamma Rabbit Polyclonal Antibody is HA500138.

What sizes are available for PP1C gamma Rabbit Polyclonal Antibody?

PP1C gamma Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PP1C gamma Rabbit Polyclonal Antibody in stock?

PP1C gamma Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PP1C gamma Rabbit Polyclonal Antibody used for?

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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