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Product details

TNF Receptor I Rabbit Polyclonal Antibody

Catalog number HA500140

Price for HA500140

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Size / count 100 µL

About this product

This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients.

Specifications

Catalog number
HA500140
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
CD120a antibody FPF antibody MGC19588 antibody p55 antibody p55-R antibody p60 antibody TBP1 antibody TBPI antibody TNF R antibody TNF R55 antibody TNF-R1 antibody TNF-RI antibody TNFAR antibody TNFR-I antibody TNFR1 antibody TNFR55 antibody TNFR60 antibody TNFRI antibody TNFRSF1a antibody TNR1A_HUMAN antibody Tumor necrosis factor receptor 1 antibody Tumor necrosis factor receptor superfamily, member 1A antibody Tumor necrosis factor receptor type 1 antibody Tumor necrosis factor receptor type I antibody Tumor necrosis factor-binding protein 1 antibody
Abbreviation
TNFRSF1A
Swiss Prot
P19438 Human
Cellular Locus
Secreted, Cell membrane, Golgi apparatus membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human TNF Receptor I aa 233-455.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
A549 cell lysate, Hela cell lysate, HepG2 cell lysate, human fallopian tube tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:100-1:500 ;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 50 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for TNF Receptor I Rabbit Polyclonal Antibody?

The catalog number for TNF Receptor I Rabbit Polyclonal Antibody is HA500140.

What sizes are available for TNF Receptor I Rabbit Polyclonal Antibody?

TNF Receptor I Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is TNF Receptor I Rabbit Polyclonal Antibody in stock?

TNF Receptor I Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is TNF Receptor I Rabbit Polyclonal Antibody used for?

This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alp

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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