RGMA Rabbit Polyclonal Antibody — image 1 of 3

Product details

RGMA Rabbit Polyclonal Antibody

Catalog number HA500148

Price for HA500148

Size / count 100 µL

About this product

Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.

Specifications

Catalog number: HA500148
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Repulsive guidance molecule A antibody RGM antibody RGM domain family member A antibody RGMA antibody RGMA_HUMAN antibody
Abbreviation: Repulsive guidance molecule A RGM domain family member A
Swiss Prot: Q96B86 Human
Cellular Locus: Cell membrane, Membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human RGMA aa 169-424.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, IF-Cell
Positive Control: Hela cell lysate, human skeletal muscle tissue lysate, MG-63, human skeletal muscle tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 50 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for RGMA Rabbit Polyclonal Antibody?

The catalog number for RGMA Rabbit Polyclonal Antibody is HA500148.

What sizes are available for RGMA Rabbit Polyclonal Antibody?

RGMA Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is RGMA Rabbit Polyclonal Antibody in stock?

RGMA Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is RGMA Rabbit Polyclonal Antibody used for?

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.