ERAB Rabbit Polyclonal Antibody

About this product

In addition to mitochondrial dehydrogenase activity, moonlights as a component of mitochondrial ribonuclease P, a complex that cleaves tRNA molecules in their 5'-ends . Together with TRMT10C/MRPP1, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity . The MRPP1-MRPP2 subcomplex catalyzes the formation of N1-methylguanine and N1-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; HSD17B10/MRPP2 acting as a non-catalytic subunit . The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme . Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.

Specifications

Catalog number

HA500150

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

17 beta hydroxysteroid dehydrogenase 10 antibody 17 beta hydroxysteroid dehydrogenase type 10 antibody 17-beta-HSD 10 antibody 17-beta-hydroxysteroid dehydrogenase 10 antibody 17b HSD10 antibody 3 hydroxy 2 methylbutyryl CoA dehydrogenase antibody 3 hydroxyacyl CoA dehydrogenase type 2 antibody 3 hydroxyacyl CoA dehydrogenase type II antibody 3-hydroxy-2-methylbutyryl-CoA dehydrogenase antibody 3-hydroxyacyl-CoA dehydrogenase type II antibody 3-hydroxyacyl-CoA dehydrogenase type-2 antibody AB binding alcohol dehydrogenase antibody ABAD antibody Ads9 antibody Amyloid beta binding polypeptide antibody Amyloid beta peptide binding alcohol dehydrogenase antibody Amyloid beta peptide binding protein antibody Amyloid beta peptide binding protein antibody CAMR antibody DUPXp11.22 antibody Endoplasmic Reticulum Amyloid Binding Protein antibody Endoplasmic reticulum associated amyloid beta peptide binding protein antibody Endoplasmic reticulum-associated amyloid beta-peptide-binding protein antibody ER associated amyloid beta-binding protein antibody ERAB antibody HADH 2 antibody HADH2 antibody HCD 2 antibody HCD2 antibody HCD2_HUMAN antibody Hsd17b10 antibody Hydroxyacyl CoA Dehydrogenase type II antibody Hydroxyacyl Coenzyme A dehydrogenase type II antibody Hydroxysteroid (17 beta) dehydrogenase 10 antibody Mental retardation X linked syndromic 11 antibody MHBD antibody Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase antibody Mitochondrial ribonuclease P protein 2 antibody Mitochondrial RNase P protein 2 antibody MRPP2 antibody MRX17 antibody SCHAD antibody SDR5C1 antibody Short chain dehydrogenase/reductase family 5C member 1 antibody Short chain L 3 hydroxyacyl CoA dehydrogenase type 2 antibody Short chain type dehydrogenase/reductase XH98G2 antibody Short-chain type dehydrogenase/reductase XH98G2 antibody Type 10 17b HSD antibody Type 10 17beta hydroxysteroid dehydrogenase antibody Type II HADH antibody XH98G2 antibody

Abbreviation

3-hydroxyacyl-CoA dehydrogenase type-2 17-beta-estradiol 17-dehydrogenase 2-methyl-3-hydroxybutyryl-CoA dehydrogenase MHBD 3-alpha- (17-beta)-hydroxysteroid dehydrogenase (NAD (+)) 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 3-hydroxyacyl-CoA dehydrogenase type II 3alpha (or 20beta)-hydroxysteroid dehydrogenase 7-alpha-hydroxysteroid dehydrogenase Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Mitochondrial ribonuclease P protein 2 Mitochondrial RNase P protein 2 Short chain dehydrogenase/reductase family 5C member 1 Short-chain type dehydrogenase/reductase XH98G2 Type II HADH

Swiss Prot

Q99714 Human, O70351 Rat

Cellular Locus

Mitochondrion.

Host

Rabbit

Species Reactivity

Human, Rat

Immunogen

Recombinant protein within human ERAB aa 1-200.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

A549 cell lysate, MCF-7 cell lysate, rat kidney tissue, human tonsil tissue, human liver tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000;IHC-P: 1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

27 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No