GNB3 Rabbit Polyclonal Antibody

About this product

Heterotrimeric guanine nucleotide-binding proteins ( G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.

Specifications

Catalog number

HA500153

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

G protein beta 3 subunit antibody GBB3_HUMAN antibody GNB3 antibody GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 antibody GTP binding regulatory protein beta 3 chain antibody Guanine nucleotide binding protein (G protein) beta polypeptide 3 antibody Guanine nucleotide binding protein G antibody Guanine nucleotide binding protein G (I)/G (S)/G (T) beta subunit 3 antibody Guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-3 antibody Hypertension associated protein antibody IG antibody SG antibody Transducin beta chain 3 antibody Tsubunit beta 3 antibody

Abbreviation

Guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-3 Transducin beta chain 3

Swiss Prot

P16520 Human, Q61011 Mouse, P52287 Rat

Cellular Locus

Cytosol.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human GNB3 aa 10-60.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

HepG2 cell lysate, Hela cell lysate, mouse brain tissue lysate, human brain tissue lysate, rat brain tissue lysate, rat kidney tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000;IHC-P: 1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

37 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No