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Product details

Spry2 Rabbit Polyclonal Antibody

Catalog number HA500170

Price for HA500170

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Size / count 100 µL

About this product

This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.

Specifications

Catalog number
HA500170
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
hSPRY 2 antibody hSPRY2 antibody MGC23039 antibody Protein sprouty homolog 2 antibody Sprouty 2 antibody Sprouty homolog 2 (Drosophila) antibody Sprouty homolog 2 antibody Sprouty2 antibody Spry 2 antibody Spry-2 antibody SPRY2 antibody SPY2_HUMAN antibody
Abbreviation
SPRY2
Swiss Prot
O43597 Human,
Cellular Locus
Ruffle membrane, cytoskeleton.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human Spry2 aa 1-180.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Rat liver tissue lysates, human liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 35 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Spry2 Rabbit Polyclonal Antibody?

The catalog number for Spry2 Rabbit Polyclonal Antibody is HA500170.

What sizes are available for Spry2 Rabbit Polyclonal Antibody?

Spry2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Spry2 Rabbit Polyclonal Antibody in stock?

Spry2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Spry2 Rabbit Polyclonal Antibody used for?

This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membran

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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