ATBF1 Rabbit Polyclonal Antibody

About this product

This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene.

Specifications

Catalog number

HA500181

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Zinc finger homeobox protein 3 AT motif-binding factor 1 AT-binding transcription factor 1 Alpha-fetoprotein enhancer-binding protein Zinc finger homeodomain protein 3 ZFH-3 ZFHX3 ATBF1 C16orf47

Abbreviation

ZFHX3

Swiss Prot

Q15911 Human, F1M4Q6 Rat

Cellular Locus

Nucleus, Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Rat

Immunogen

Recombinant protein within human ATBF1 aa 1,800-2,000.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

Rat esophagus tissue, human colon tissue, human breast carcinoma tissue, human stomach carcinoma tissue.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 for recombinant protein; 1:500 for endogenous lysates (predicted) ;IHC-P: 1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

404/306 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No