NMDAR2B Rabbit Polyclonal Antibody

About this product

This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia.

Specifications

Catalog number

HA500208

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

AW490526 antibody EIEE27 antibody Glutamate [NMDA] receptor subunit epsilon 2 antibody Glutamate [NMDA] receptor subunit epsilon-2 antibody Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody Glutamate receptor ionotropic NMDA2B antibody Glutamate receptor subunit epsilon 2 antibody Glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody GRIN 2B antibody GRIN2B antibody hNR 3 antibody hNR3 antibody MGC142178 antibody MGC142180 antibody MRD6 antibody N methyl D asparate receptor channel subunit epsilon 2 antibody N methyl D aspartate receptor subtype 2B antibody N methyl D aspartate receptor subunit 2B antibody N methyl D aspartate receptor subunit 3 antibody N-methyl D-aspartate receptor subtype 2B antibody N-methyl-D-aspartate receptor subunit 3 antibody NMDA NR2B antibody NMDA R2B antibody NMDAR2B antibody NMDE2 antibody NMDE2_HUMAN antibody NME2 antibody NR2B antibody NR3 antibody GluN2B

Abbreviation

GRIN2B

Swiss Prot

Q13224 Human, Q01097 Mouse, Q00960 Rat

Cellular Locus

Late endosome, cytoskeleton, cell membrane, postsynaptic cell membrane, lysosome.

Host

Rabbit

Species Reactivity

Mouse, Rat, Human

Immunogen

Recombinant protein within human NMDAR2B aa 1100-1300 / 1484.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Mouse brain tissue lysate, rat brain tissue lysate, mouse hippocampus tissue lysate, A549, rat cerebellum tissue, MG-63.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:100-1:500 ;FC: 1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

predicated 166 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No