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Product details

SREBP1 Rabbit Polyclonal Antibody

Catalog number HA500210

Price for HA500210

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Size / count 100 µL

About this product

This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively.

Specifications

Catalog number
HA500210
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
ADD 1 antibody bHLHd1 antibody Class D basic helix-loop-helix protein 1 antibody D630008H06 antibody Processed sterol regulatory element-binding protein 1 antibody SRBP1_HUMAN antibody SREBF 1 antibody SREBF1 antibody SREBP 1 antibody SREBP 1c antibody SREBP-1 antibody SREBP1 antibody Sterol regulatory element binding protein 1 antibody Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1 antibody Sterol regulatory element binding transcription factor 1 antibody Sterol regulatory element-binding transcription factor 1 antibody
Abbreviation
SREBF1
Swiss Prot
P36956 Human, Q9WTN3 Mouse
Cellular Locus
Endoplasmic reticulum membrane, Golgi apparatus membrane, COPII-coated vesicle membrane; Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within N-terminal human SREBP1 from aa25-aa55.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HepG2 cell lysate, mouse heart tissue lysate, mouse liver tissue lysate, 293 cell lysate, Jurkat cell lysate, A549 cell lysate, Hela, human lung tissue, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
122 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for SREBP1 Rabbit Polyclonal Antibody?

The catalog number for SREBP1 Rabbit Polyclonal Antibody is HA500210.

What sizes are available for SREBP1 Rabbit Polyclonal Antibody?

SREBP1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is SREBP1 Rabbit Polyclonal Antibody in stock?

SREBP1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is SREBP1 Rabbit Polyclonal Antibody used for?

This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded pro

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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