PRDC Rabbit Polyclonal Antibody — image 1 of 2

Product details

PRDC Rabbit Polyclonal Antibody

Catalog number HA500225

Price for HA500225

Size / count 100 µL

About this product

PRDC (protein related to DAN and Cerberus) is a secreted cysteine knot-containing BMP antagonist belonging to the Cerberus/DAN (CAN) family. Mammalian CAN family members, including Gremlin, Dan, Cerberus, COCO, SOST, and USAG-1, have the conserved 6 cysteine residues that form a cysteine knot, and two additional cysteine residues located in the loops of the cysteine knot, which form an additional intrasubunit disulfide bond. PRDC acts as a specific BMP antagonist, binding to and blocking signaling induced by BMP-2 or -4, but not Activin or TGF-beta. Thus, PRDC expression in the ovary could be involved in follicular development by antagonizing the inhibitory effects of BMPs on FSH stimulation of progesterone

Specifications

Catalog number: HA500225
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: BMP antagonist 2 antibody CKTSF1B2 antibody Cysteine knot superfamily 1 antibody Cysteine knot superfamily 1 BMP antagonist 2 antibody DAN domain family member 3 antibody DAND 3 antibody DAND3 antibody GREM 2 antibody Grem2 antibody GREM2_HUMAN antibody Gremlin 2 antibody Gremlin 2 cysteine knot superfamily homolog antibody Gremlin-2 antibody Gremlin2 antibody PRDC antibody Protein related to DAN and cerberus antibody
Abbreviation: GREM2
Swiss Prot: Q9H772 Human
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within human PRDC aa 50-100.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, FC
Positive Control: CAL62 cell lysates, SH-SY5Y.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;FC: 1:200-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 19 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PRDC Rabbit Polyclonal Antibody?

The catalog number for PRDC Rabbit Polyclonal Antibody is HA500225.

What sizes are available for PRDC Rabbit Polyclonal Antibody?

PRDC Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PRDC Rabbit Polyclonal Antibody in stock?

PRDC Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PRDC Rabbit Polyclonal Antibody used for?

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.