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Product details

EDN3 Rabbit Polyclonal Antibody

Catalog number HA500241

Price for HA500241

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Size / count 100 µL

About this product

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

Catalog number
HA500241
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
EDN3 antibody EDN3_HUMAN antibody Endothelin 3 antibody Endothelin-3 antibody ET 3 antibody ET-3 antibody PPET3 antibody Preproendothelin 3 antibody Preproendothelin-3 antibody
Abbreviation
EDN3
Swiss Prot
P14138 Human, P48299 Mouse, P13207 Rat
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human Endothelin 3 aa 80-130.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Raji cell lysate, 293 cell lysate, MCF-7 cell lysate, SW480 cell lysate, MG-63, rat placenta tissue, human placenta tissue, mouse placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:100;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 25 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for EDN3 Rabbit Polyclonal Antibody?

The catalog number for EDN3 Rabbit Polyclonal Antibody is HA500241.

What sizes are available for EDN3 Rabbit Polyclonal Antibody?

EDN3 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is EDN3 Rabbit Polyclonal Antibody in stock?

EDN3 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is EDN3 Rabbit Polyclonal Antibody used for?

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligan

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

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