TTK Rabbit Polyclonal Antibody

About this product

This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

Specifications

Catalog number

HA500249

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

cancer/testis antigen 96 antibody CT96 antibody Dual specificity protein kinase TTK antibody ECSTY kinase antibody ESK antibody FLJ38280 antibody hMPS1 antibody Monopolar Spindle 1 Like 1 antibody MPH1 antibody Mps 1 antibody MPS1L1 antibody Phosphotyrosine Picked Threonine Kinase antibody Phosphotyrosine picked threonine-protein kinase antibody PYT antibody RP3-357D13.2 antibody ttk antibody TTK Protein Kinase antibody TTK_HUMAN antibody

Abbreviation

TTK

Swiss Prot

P33981 Human

Cellular Locus

Spindle, nucleus, cytoplasm, kinetochore, membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human TTK aa 1-300.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

Human placenta tissue lysates, human lung tissue, human thyroid tissue, human colon carcinoma tissue, human skin tissue, human breast carcinoma tissue, human esophagus tissue, human placenta tissue, SH-SY5Y, MG-63.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000;IHC-P: 1:100;IF-Cell: 1:50;FC: 1:500-1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 1% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 97 kDa.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No