PRDM1 Rabbit Polyclonal Antibody

About this product

Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (By similarity). Binds specifically to the PRDI element in the promoter of the beta-interferon gene . Drives the maturation of B-lymphocytes into Ig secreting cells . Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions (By similarity).

Specifications

Catalog number

HA500255

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

B Lymphocyte Induced Maturation Protein 1 antibody Beta interferon gene positive regulatory domain I binding factor antibody Beta-interferon gene positive regulatory domain I-binding factor antibody BLIMP-1 antibody BLIMP1 antibody Positive Regulatory Domain I Binding Factor 1 antibody Positive regulatory domain I-binding factor 1 antibody PR Domain Containing 1 antibody PR domain containing 1 with ZNF domain antibody PR domain containing 1 with ZNF domain isoform 2 antibody PR domain containing protein 1 antibody PR domain zinc finger protein 1 antibody PR domain-containing protein 1 antibody PRDI BF1 antibody PRDI binding factor 1 antibody PRDI-BF1 antibody PRDI-binding factor 1 antibody PRDM 1 antibody Prdm1 antibody PRDM1_HUMAN antibody

Abbreviation

PR domain zinc finger protein 1 (EC:2.1.1.-) BLIMP-1 Beta-interferon gene positive regulatory domain I-binding factor PR domain-containing protein 1 Positive regulatory domain I-binding factor 1 PRDI-BF1 PRDI-binding factor 1

Swiss Prot

O75626 Human, Q60636 Mouse

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human aa 770-825 / 825.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

IHC-P, FC

Positive Control

Rat cervix tissue, human skin tissue, human esophagus tissue, mouse esophagus tissue, PANC-1.

Concentration

1 mg/mL

Dilution

IHC-P: 1:100-1:500;FC: 1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

92 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No