PP-X Rabbit Polyclonal Antibody — image 1 of 2

Product details

PP-X Rabbit Polyclonal Antibody

Catalog number HA500276

Price for HA500276

Size / count 100 µL

About this product

Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on Ser-140 (gamma-H2AX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.

Specifications

Catalog number: HA500276
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: PP X antibody PP-X antibody Pp4 antibody PP4C antibody PP4C_HUMAN antibody PPH3 antibody PPP4 antibody ppp4c antibody PPX antibody protein phosphatase 4 (formerly X), catalytic subunit antibody Protein phosphatase 4 catalytic subunit antibody Protein phosphatase X antibody protein phosphatase X, catalytic subunit antibody Serine/threonine protein phosphatase 4 catalytic subunit antibody Serine/threonine-protein phosphatase 4 catalytic subunit antibody
Abbreviation: PPP4C
Swiss Prot: P60510 Human
Cellular Locus: Centrosome, Nucleus, Cytoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human PP-X aa 151-307 / 307.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: 293T cell lysates, human colon tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 35 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PP-X Rabbit Polyclonal Antibody?

The catalog number for PP-X Rabbit Polyclonal Antibody is HA500276.

What sizes are available for PP-X Rabbit Polyclonal Antibody?

PP-X Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PP-X Rabbit Polyclonal Antibody in stock?

PP-X Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PP-X Rabbit Polyclonal Antibody used for?

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.