CCR3 Rabbit Polyclonal Antibody — image 1 of 2

Product details

CCR3 Rabbit Polyclonal Antibody

Catalog number HA500279

Price for HA500279

Size / count 100 µL

About this product

C-C chemokine receptor type 3 is a protein that in humans is encoded by the CCR3 gene. CCR3 has also recently been designated CD193 (cluster of differentiation 193). The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway, and possibly at sites of parasitic infection. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described.

Specifications

Catalog number: HA500279
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: B chemokine receptor antibody b-chemokine receptor antibody C C chemokine receptor type 3 antibody C C CKR 3 antibody C-C chemokine receptor type 3 antibody C-C CKR-3 antibody CC chemokine receptor 3 antibody CC chemokine receptor type 3 antibody CC CKR 3 antibody CC R3 antibody CC-CKR-3 antibody CCCKR3 antibody CCR 3 antibody CCR-3 antibody CCR3 antibody CCR3_HUMAN antibody CD 193 antibody CD193 antibody CD193 antigen antibody Chemokine (C C motif) receptor 3 antibody chemokine (C-C motif) receptor 3 antibody Chemokine (CC) receptor 1 like 2 antibody Chemokine CC motif receptor 3 antibody Chemokine receptor 3 antibody CK R3 antibody CKR 3 antibody CKR3 antibody CMKB R3 antibody CMKBR 3 antibody CMKBR1L2 antibody CMKBR3 antibody Eosinophil CC chemokine receptor 3 antibody Eosinophil eotaxin receptor antibody Eotaxin receptor antibody Macrophage inflammatory protein 1 alpha receptor like 2 antibody MGC102841 antibody MIP1 Alpha RL2 antibody
Abbreviation: C-C chemokine receptor type 3 C C CKR3 C-C CKR-3 CC-CKR-3 CCR-3 CCR3 CKR 3 CKR3 Eosinophil eotaxin receptor CD193 CMKBR3
Swiss Prot: P51677 Human
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within human CCR3 aa 1-34 / 355.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell
Positive Control: K562 cell lysate, Jurkat cell lysate, HepG2 cell lysate, SW480.
Concentration: 1 mg/mL
Dilution: WB: 1:500;IF-Cell:1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 41 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

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