GCSF Receptor Rabbit Polyclonal Antibody — image 1 of 2

Product details

GCSF Receptor Rabbit Polyclonal Antibody

Catalog number HA500282

Price for HA500282

Size / count 100 µL

About this product

Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. Mutations in CSF3R acquired in multipotent hematopoietic progenitor cells and resulting in truncated hyper-responsive forms of the receptor, have been identified in most cases of severe congenital neutropenia (SCN). Patients carrying these mutations are at risk for developing myelodysplastic syndromes and/or acute myeloid leukemia. Constitutive mutations leading to hyporesponsive forms of the receptor are responsible for the refractoriness to CSF3 treatment observed in some SCN patients.

Specifications

Catalog number: HA500282
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CD 114 antibody CD114 antibody CD114 antigen antibody Colony stimulating factor 3 receptor (granulocyte) antibody Colony stimulating factor 3 receptor antibody CSF 3R antibody CSF3R antibody CSF3R_HUMAN antibody Csfgr antibody G CSF R antibody G-CSF receptor antibody G-CSF-R antibody GCSFR antibody Granulocyte colony stimulating factor receptor antibody Granulocyte colony-stimulating factor receptor antibody OTTHUMP00000009703 antibody OTTHUMP00000009704 antibody OTTHUMP00000009705 antibody
Abbreviation: CSF3R
Swiss Prot: Q99062 Human
Cellular Locus: Secreted, Cell membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within human GCSF Receptor aa 787-836.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: HL-60 cell lysate, THP-1 cell lysate, SH-SY5Y cell lysate, Hela, THP-1.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;FC: 1:500-1:1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 92 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for GCSF Receptor Rabbit Polyclonal Antibody?

The catalog number for GCSF Receptor Rabbit Polyclonal Antibody is HA500282.

What sizes are available for GCSF Receptor Rabbit Polyclonal Antibody?

GCSF Receptor Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is GCSF Receptor Rabbit Polyclonal Antibody in stock?

GCSF Receptor Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is GCSF Receptor Rabbit Polyclonal Antibody used for?

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.