NEDD1 Rabbit Polyclonal Antibody — image 1 of 3

Product details

NEDD1 Rabbit Polyclonal Antibody

Catalog number HA500294

Price for HA500294

Size / count 100 µL

About this product

NEDD1 (neural precursor cell expressed, developmentally down-regulated 1), also known as GCP-WD, is a homolog of the Drosophila protein known as Dgp71WD. It is a ubiquitously expressed, evolutionarily conserved protein and contains eight WD40 repeats and a coiled coil domain at the C-terminus. NEDD1 is a subunit of the γ-tubulin ring complex (γTuRC) and plays an important role in mitosis. During mitosis NEDD1 is phosphorylated and functions in forming the association of γ-tubulin with the spindle. The state of phosphorylation of NEDD1 is also important for determining its cellular localization. NEDD1 is responsible for targeting γTuRC to the centrosome and spindle and is therefore required for centrosomal and chromatin-mediated microtubule nucleation. The inhibition of NEDD1 results in the loss of γTuRC from the centrosome and a sequential loss of microtubule nucleation. Due to its critical role in mitosis, NEDD1 may be a potential target for anticancer therapies.

Specifications

Catalog number: HA500294
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: FLJ35902 antibody GCP WD antibody NEDD-1 antibody NEDD1 antibody NEDD1_HUMAN antibody Neural precursor cell expressed developmentally down-regulated protein 1 antibody Neural precursor cell expressed, developmentally down regulated gene 1 antibody Protein NEDD1 antibody TUBGCP7 antibody
Abbreviation: NEDD1
Swiss Prot: Q8NHV4 Human, P33215 Mouse
Cellular Locus: Centrosome.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human NEDD1 aa 1-200 / 660.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: Mouse lung lysates, human skin tissue, SiHa.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500 ;FC: 1:100-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 72 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for NEDD1 Rabbit Polyclonal Antibody?

The catalog number for NEDD1 Rabbit Polyclonal Antibody is HA500294.

What sizes are available for NEDD1 Rabbit Polyclonal Antibody?

NEDD1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is NEDD1 Rabbit Polyclonal Antibody in stock?

NEDD1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is NEDD1 Rabbit Polyclonal Antibody used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.