PRR5 Rabbit Polyclonal Antibody

Catalog number HA500295

Price for HA500295

Size / count 100 µL

About this product

Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. PRR5 plays an important role in regulation of PDGFRB expression and in modulation of platelet-derived growth factor signaling. May act as a tumor suppressor in breast cancer.

Specifications

Catalog number: HA500295
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Arhgap8 antibody AU043908 antibody C030017C09Rik antibody C78947 antibody FLJ20185 antibody FLJ20185k antibody MGC109513 antibody MGC32512 antibody PP610 antibody Proline rich 5 (renal) antibody Proline-rich protein 5 antibody Protein observed with Rictor-1 antibody Protor-1 antibody PROTOR1 antibody PRR5 antibody PRR5_HUMAN antibody PTOR1 antibody Rho GTPase activating protein 8 antibody RP1-181C9.3 antibody
Abbreviation: Proline-rich protein 5 Protein observed with Rictor-1 Protor-1 PP610 PROTOR1 RR5
Swiss Prot: P85299 Human, Q812A5 Mouse, Q5FVG6 Rat
Cellular Locus: Cytosol.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human Protor-1 aa 200-388 / 388.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB
Positive Control: MCF-7 cell lysate, mouse liver tissue lysate, rat liver tissue lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 42/31/32/45 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PRR5 Rabbit Polyclonal Antibody?

The catalog number for PRR5 Rabbit Polyclonal Antibody is HA500295.

What sizes are available for PRR5 Rabbit Polyclonal Antibody?

PRR5 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PRR5 Rabbit Polyclonal Antibody in stock?

PRR5 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PRR5 Rabbit Polyclonal Antibody used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.