MyT1L Rabbit Polyclonal Antibody — image 1 of 3

Product details

MyT1L Rabbit Polyclonal Antibody

Catalog number HA500297

Price for HA500297

Size / count 100 µL

About this product

Transcription factor that plays a key role in neuronal differentiation by specifically repressing expression of non-neuronal genes during neuron differentiation. In contrast to other transcription repressors that inhibit specific lineages, mediates repression of multiple differentiation programs. Also represses expression of negative regulators of neurogenesis, such as members of the Notch signaling pathway, including HES1. The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Directly binds the 5'-AAGTT-3' core motif present on the promoter of target genes and represses transcription by recruiting a multiprotein complex containing SIN3B. The 5'-AAGTT-3' core motif is absent from the promoter of neural genes.

Specifications

Catalog number: HA500297
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Myelin transcription factor 1-like protein antibody MyT1-L antibody MyT1L antibody MYT1L_HUMAN antibody neural zinc finger transcription factor 1 antibody
Abbreviation: Myelin transcription factor 1-like protein MyT1-L MyT1L
Swiss Prot: Q9UL68 Human, P97500 Mouse
Cellular Locus: Chromosome, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human MyT1L aa 200-400 / 1186.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: SHSY5Y cell lysates, mouse cerebellum tissue, mouse brain tissue, SH-SY5Y.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1000;IHC-P: 1:100-1:500;FC: 1:100-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 133 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for MyT1L Rabbit Polyclonal Antibody?

The catalog number for MyT1L Rabbit Polyclonal Antibody is HA500297.

What sizes are available for MyT1L Rabbit Polyclonal Antibody?

MyT1L Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is MyT1L Rabbit Polyclonal Antibody in stock?

MyT1L Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is MyT1L Rabbit Polyclonal Antibody used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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