CX3CL1 Rabbit Polyclonal Antibody

About this product

Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 . Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 . The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium.

Specifications

Catalog number

HA500304

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

A 152E5.2 antibody AB030188 antibody ABCD 3 antibody ABCD3 antibody AI848747 antibody C-X3-C motif chemokine 1 antibody C3Xkine antibody Chemokine (C-X3-C motif) ligand 1 antibody Chemokine C X3 C motif ligand 1 antibody Chemokine CX3C Motif Ligand 1 antibody CX3C membrane anchored chemokine antibody CX3C membrane-anchored chemokine antibody Cx3cl1 antibody CXC 3 antibody CXC3 antibody CXC3C antibody D8Bwg0439e antibody FKN antibody Fractalkine antibody Neurotactin antibody NTN antibody NTT antibody Processed fractalkine antibody SCYD 1 antibody SCYD1 antibody Small inducible cytokine D1 antibody Small inducible cytokine subfamily D (Cys X3 Cys) member 1 antibody small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin) antibody Small inducible cytokine subfamily D member 1 antibody Small-inducible cytokine D1 antibody X3CL1_HUMAN antibody

Abbreviation

Processed fractalkine C-X3-C motif chemokine 1 CX3C membrane-anchored chemokine Neurotactin Fractalkine Small-inducible cytokine D1

Swiss Prot

P78423 Human

Cellular Locus

Cell membrane, Membrane, Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human CX3CL1 aa 25-341 / 397 (Extracellular).

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P

Positive Control

SK-BR-3 cell lysate, HepG2 cell lysate, human skin tissue, human breast carcinoma tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

42 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No