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Product details

Proteasome 20S beta 6 Rabbit Polyclonal Antibody

Catalog number HA500349

Price for HA500349

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Size / count 100 µL

About this product

In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S Proteasome. The 26S Proteasome is a protease complex that selectively breaks down proteins that have been modified by polyubiquitin chains. It is made up of two multisubunit complexes: the 20S Proteasome chamber, which serves as the proteolytic core of the complex and two 19S regulatory particles which recognize and unfold ubiquitinated proteins. The 20S Proteasome chamber contains α subunits (which are structural) and β subunits (which are predominantly catalytic). The outer two rings in the proteasome consist of seven α subunits each, and the inner two rings each consist of seven β subunits. PSMB6 (proteasome (prosome, macropain) subunit, β type, 6), also known as LMPY (PSY large multifunctional protease Y), macropain δ chain, proteasome δ chain or proteasome subunit Y, is a β subunit of the 20S Proteasome and, upon stimulation with IFN-γ, can be displaced by LMP2.

Specifications

Catalog number
HA500349
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
DELTA antibody LMPY antibody Macropain delta chain antibody MGC5169 antibody Multicatalytic endopeptidase complex delta chain antibody Proteasome (prosome macropain) subunit beta type 6 antibody Proteasome beta 6 subunit antibody Proteasome catalytic subunit 1 antibody Proteasome delta chain antibody Proteasome subunit beta 6 antibody Proteasome subunit beta type 6 antibody Proteasome subunit beta type-6 antibody Proteasome subunit delta antibody Proteasome subunit Y antibody PSB6_HUMAN antibody PSMB6 antibody PSY large multifunctional protease Y antibody Y antibody
Abbreviation
PSMB6
Swiss Prot
P28072 Human, Q60692 Mouse, P28073 Rat
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Proteasome 20S beta 6 aa 21-239 / 239.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Hela cell lysate, Jurkat cell lysate, mouse colon tissue lysate, mouse kidney tissue lysate, rat kidney tissue lysate, NIH/3T3, mouse brain tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:200;IHC-P: 1:1,000;FC: 1:500-1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 25 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Proteasome 20S beta 6 Rabbit Polyclonal Antibody?

The catalog number for Proteasome 20S beta 6 Rabbit Polyclonal Antibody is HA500349.

What sizes are available for Proteasome 20S beta 6 Rabbit Polyclonal Antibody?

Proteasome 20S beta 6 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Proteasome 20S beta 6 Rabbit Polyclonal Antibody in stock?

Proteasome 20S beta 6 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Proteasome 20S beta 6 Rabbit Polyclonal Antibody used for?

In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S Proteasome. The 26S Proteasome is a protease complex that selectively breaks down proteins that have been modified by polyubiquitin chains. It is made up of two mult

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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