• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Beta TRCP Rabbit Polyclonal Antibody

Catalog number HA500358

Price for HA500358

Sign In for Pricing

Size / count 100 µL

About this product

F-box/WD repeat-containing protein 1A (FBXW1A) also known as βTrCP1 or Fbxw1 or hsSlimb or pIkappaBalpha-E3 receptor subunit is a protein that in humans is encoded by the BTRC (beta-transducin repeat containing) gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 residue structural motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (Skp1-Cul1-F-box protein), which often, but not always, recognize substrates in a phosphorylation-dependent manner. F-box proteins are divided into 3 classes: Fbxws containing WD40 repeats; Fbxls containing leucine-rich repeats; Fbxos containing either "other" protein–protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxw class as, in addition to an F-box, this protein contains multiple WD40 repeats. This protein is homologous to Xenopus βTrCP, yeast Met30, Neurospora Scon2 and Drosophila Slimb. In mammals, in addition to βTrCP1, a paralog protein (called βTrCP2 or FBXW11) also exists, but, so far, their functions appear redundant and indistinguishable.

Specifications

Catalog number
HA500358
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Beta transducin repeat containing E3 ubiquitin protein ligase antibody beta TrCP1 antibody beta-transducin repeat containing antibody BETA-TRCP antibody betaTrCP antibody btrC antibody bTrCP antibody bTrCP1 antibody E3RSIkappaB antibody F box and WD repeat protein 1B antibody F box and WD repeats protein beta TrCP antibody F-box and WD repeats protein beta-TrCP antibody F-box/WD repeat protein 1A antibody F-box/WD repeat-containing protein 1A antibody FBW1A antibody FBW1A_HUMAN antibody FBXW1 antibody FBXW1A antibody FWD1 antibody HOS antibody mKIAA4123 antibody pIkappaBalpha-E3 receptor subunit antibody Slimb antibody
Abbreviation
BTRC
Swiss Prot
Q9Y297 Human, Q3ULA2 Mouse,
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Beta TRCP aa 1-200 / 605.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HepG2 cell lysate, Hela cell lysate, 293T cell lysate, mouse testis tissue lysate, rat brain tissue lysate, mouse brain tissue lysate, A549, human colon tissue, mouse large intestine tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000;IF-Cell: 1:100;IHC-P: 1:1,000-1:2,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 69 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Beta TRCP Rabbit Polyclonal Antibody?

The catalog number for Beta TRCP Rabbit Polyclonal Antibody is HA500358.

What sizes are available for Beta TRCP Rabbit Polyclonal Antibody?

Beta TRCP Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Beta TRCP Rabbit Polyclonal Antibody in stock?

Beta TRCP Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Beta TRCP Rabbit Polyclonal Antibody used for?

F-box/WD repeat-containing protein 1A (FBXW1A) also known as βTrCP1 or Fbxw1 or hsSlimb or pIkappaBalpha-E3 receptor subunit is a protein that in humans is encoded by the BTRC (beta-transducin repeat containing) gene. This gene encodes a member of the F-box protein family which is characterized by a

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

You Might Also Like
CD8 (RIV11), CF555 conjugate, 0.1mg/mL
CD8 (RIV11), CF555 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC550333-500
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040994-100
CD5 (Cris-1), CF740 conjugate, 0.1mg/mL
CD5 (Cris-1), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740176-500
Cytokeratin 10 (KRT10/844), CF488A conjugate, 0.1mg/mL
Cytokeratin 10 (KRT10/844), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880844-500
Vimentin (VM1170), CF647 conjugate, 0.1mg/mL
Vimentin (VM1170), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471170-500
CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (rLPFS2/1611), CF405S conjugate, 0.1mg/mL
CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (rLPFS2/1611), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041976-500
MCM7 (Proliferation Marker) (MCM7/1468), CF568 conjugate, 0.1mg/mL
MCM7 (Proliferation Marker) (MCM7/1468), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC681468-500
Moesin (MSN/492), CF405S conjugate, 0.1mg/mL
Moesin (MSN/492), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040492-500