IFNGR2 Rabbit Polyclonal Antibody

Catalog number HA500363

Price for HA500363

Size / count 100 µL

About this product

Interferon gamma receptor 2 also known as IFN-γR2 is a protein which in humans is encoded by the IFNGR2 gene. This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a multimer of two IFN-γR1 chains (encoded by IFNGR1) and two IFN-γR2 chains. Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding. Defects in IFNGR2 are a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. All known mutations in IFNGR2 are collected in the IFNGR2 mutation database.

Specifications

Catalog number: HA500363
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Interferon gamma receptor 2Imported antibody IFN-gamma receptor 2 antibody IFN-gamma-R2 antibody Interferon gamma receptor accessory factor 1 antibody AF-1 antibody Interferon gamma receptor beta-chain antibody IFN-gamma-R-beta antibody Interferon gamma transducer 1 antibody IFNGR2 antibody IFNGT1 antibody
Abbreviation: Interferon gamma receptor 2Imported IFN-gamma receptor 2 IFN-gamma-R2 Interferon gamma receptor accessory factor 1 AF-1 Interferon gamma receptor beta-chain IFN-gamma-R-beta Interferon gamma transducer 1 IFNGR2 IFNGT1
Swiss Prot: P38484 Human,
Cellular Locus: Endoplasmic reticulum, Plasma membrane, Golgi apparatus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human INGR2 22-71.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell
Positive Control: Jurkat cell lysate, Hela cell lysate, A431 cell lysate, human skeletal muscle tissue lysates, SH-SY5Y.
Concentration: 1.8 mg/mL
Dilution: WB: 1:500 ;IF-Cell: 1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 38 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for IFNGR2 Rabbit Polyclonal Antibody?

The catalog number for IFNGR2 Rabbit Polyclonal Antibody is HA500363.

What sizes are available for IFNGR2 Rabbit Polyclonal Antibody?

IFNGR2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is IFNGR2 Rabbit Polyclonal Antibody in stock?

IFNGR2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is IFNGR2 Rabbit Polyclonal Antibody used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.