PSME4 Rabbit Polyclonal Antibody

Catalog number HA500375

Price for HA500375

Size / count 100 µL

About this product

Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks.

Specifications

Catalog number: HA500375
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: KIAA0077 antibody PA200 antibody Proteasome Activator 200 kDa antibody Proteasome activator complex subunit 4 antibody Proteasome activator PA200 antibody PSME 4 antibody psme4 antibody PSME4_HUMAN antibody
Abbreviation: Proteasome activator complex subunit 4 Proteasome activator PA200 PSME4 KIAA0077
Swiss Prot: Q14997 Human, Q5SSW2 Mouse,
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human PSME4 aa 1,550-1,843.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: 293T cell lysate, Hela cell lysate, Jurkat cell lysate, RAW264.7 cell lysate, rat skeletal muscle tissue lysate, rat liver tissue, mouse liver tissue.
Concentration: 1.57 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 211 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PSME4 Rabbit Polyclonal Antibody?

The catalog number for PSME4 Rabbit Polyclonal Antibody is HA500375.

What sizes are available for PSME4 Rabbit Polyclonal Antibody?

PSME4 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PSME4 Rabbit Polyclonal Antibody in stock?

PSME4 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PSME4 Rabbit Polyclonal Antibody used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.