PPP2R1B Rabbit Polyclonal Antibody

About this product

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform is an enzyme that in humans is encoded by the PPP2R1B gene. This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene.

Specifications

Catalog number

HA500383

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

2AAB_HUMAN antibody beta isoform of regulatory subunit A, protein phosphatase 2 antibody PP2A A beta antibody PP2A subunit A isoform PR65-beta antibody PP2A subunit A isoform R1-beta antibody PP2A, subunit A, PR65 beta isoform antibody PP2A, subunit A, R1 beta isoform antibody PPP2R1B antibody PPP4R1 antibody PR65B antibody protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform antibody protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform antibody Protein phosphatase 2, regulatory subunit A, beta antibody Protein phosphatase 2, structural/regulatory subunit A, beta antibody protein phosphatase 2, structural/regulatory subunit A, beta isoform antibody serine/threonine protein phosphatase 2A 65 kDa regulatory subunit A, beta isoform antibody serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, beta isoform antibody Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform antibody

Abbreviation

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform PP2A subunit A isoform PR65-beta PP2A subunit A isoform R1-beta PPP2R1B

Swiss Prot

P30154 Human, Q7TNP2 Mouse, Q4QQT4 Rat

Cellular Locus

Secreted, Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human PPP2R1B aa 100-350.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

Jurkat cell lysate, Hela cell lysate, RAW264.7 cell lysate, 293 cell lysate, rat brain liver tissue lysate, rat liver tissue lysate, mouse brain tissue lysate, human pancreas tissue, SiHa.

Concentration

2.4 mg/mL

Dilution

WB: 1:2,000 ;IHC-P: 1:600 ;IF-Cell: 1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 66 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No