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Product details

PLCB2 Rabbit Polyclonal Antibody

Catalog number HA500399

Price for HA500399

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Size / count 100 µL

About this product

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene. The gene codes for the enzyme phospholipase C β2. The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11, as well as G-beta gamma subunits. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.

Specifications

Catalog number
HA500399
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
1-phosphatidylinositol-4 antibody 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 antibody 5-bisphosphate phosphodiesterase beta-2 antibody FLJ38135 antibody Phosphoinositide phospholipase C-beta-2 antibody Phospholipase C-beta-2 antibody PLC-beta-2 antibody Plcb2 antibody PLCB2_HUMAN antibody
Abbreviation
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 Phosphoinositide phospholipase C-beta-2 Phospholipase C-beta-2 PLC-beta-2 PLCB2
Swiss Prot
Q00722 Human
Cellular Locus
Cytosol.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human PLCB2 aa 950-1185.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
HL-60 cell lysate, THP-1 cell lysate, SiHa.
Concentration
1.99 mg/mL
Dilution
WB: 1:2,000;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 134 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for PLCB2 Rabbit Polyclonal Antibody?

The catalog number for PLCB2 Rabbit Polyclonal Antibody is HA500399.

What sizes are available for PLCB2 Rabbit Polyclonal Antibody?

PLCB2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PLCB2 Rabbit Polyclonal Antibody in stock?

PLCB2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PLCB2 Rabbit Polyclonal Antibody used for?

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene. The gene codes for the enzyme phospholipase C β2. The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphat

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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