PIAS4 Rabbit Polyclonal Antibody

Catalog number HA500411

Price for HA500411

Size / count 100 µL

About this product

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation. Binds to AT-rich DNA sequences, known as matrix or scaffold attachment regions (MARs/SARs). Catalyzes conjugation of SUMO2 to KAT5 in response to DNA damage, facilitating repair of DNA double-strand breaks (DSBs) via homologous recombination (HR). Highly expressed in testis and, at lower levels, in spleen, prostate, ovary, colon and peripheral blood leukocytes.

Specifications

Catalog number: HA500411
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: E3 SUMO protein ligase PIAS4 antibody E3 SUMO-protein ligase PIAS4 antibody FLJ12419 antibody MGC35296 antibody PAIASgamma antibody PIAS 4 antibody PIAS gamma antibody PIAS-gamma antibody Pias4 antibody PIAS4_HUMAN antibody PIASG antibody PIASgamma antibody PIASy antibody Protein inhibitor of activated STAT 4 antibody Protein inhibitor of activated STAT protein 4 antibody Protein inhibitor of activated STAT protein gamma antibody Protein inhibitor of activated STAT protein PIASy antibody Zinc finger MIZ type containing 6 antibody ZMIZ 6 antibody ZMIZ6 antibody
Abbreviation: E3 SUMO-protein ligase PIAS4 PIASy Protein inhibitor of activated STAT protein 4 Protein inhibitor of activated STAT protein gamma (PIAS-gamma) PIAS4 PIASG
Swiss Prot: Q8N2W9 Human, Q3UGQ2 Mouse
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human PIAS4 180-250.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: Mouse testis tissue lysate, rat kidney tissue lysate, human kidney tissue.
Concentration: 1.83 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:600
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 56.5 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PIAS4 Rabbit Polyclonal Antibody?

The catalog number for PIAS4 Rabbit Polyclonal Antibody is HA500411.

What sizes are available for PIAS4 Rabbit Polyclonal Antibody?

PIAS4 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PIAS4 Rabbit Polyclonal Antibody in stock?

PIAS4 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PIAS4 Rabbit Polyclonal Antibody used for?

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.