TBP-1 Rabbit Polyclonal Antibody

About this product

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides. Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits, a base containing 6 ATPases including PSMC3 and few additional components.

Specifications

Catalog number

HA500413

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

26S protease regulatory subunit 6A antibody 26S proteasome AAA-ATPase subunit RPT5 antibody Human immunodeficiency virus tat transactivator binding protein 1 antibody MGC8487 antibody Proteasome (prosome macropain) 26S subunit ATPase 3 antibody Proteasome 26S ATPase subunit 3 antibody Proteasome 26S subunit ATPase 3 antibody Proteasome subunit P50 antibody PRS6A_HUMAN antibody PSMC 3 antibody PSMC3 antibody Tat binding protein 1 antibody TAT-binding protein 1 antibody TBP-1 antibody TBP1 antibody

Abbreviation

26S proteasome regulatory subunit 6A 26S proteasome AAA-ATPase subunit RPT5 Proteasome 26S subunit ATPase 3 Proteasome subunit P50 Tat-binding protein 1 TBP-1 PSMC3 TBP1

Swiss Prot

P17980 Human, O88685 Mouse

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant protein within human TBP-1 aa 1-250.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

293T cell lysate, Hela cell lysate, MCF-7 cell lysate, human ovarian tumor tissue, human pancreas tissue, 293T.

Concentration

1.7 mg/mL

Dilution

WB: 1:5,000 ;IHC-P: 1:1,000 ;FC: 1:500-1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 49 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No