IRS-2 Rabbit Polyclonal Antibody

Catalog number HA500415

Price for HA500415

Size / count 100 µL

About this product

Insulin receptor substrate 2 is a protein that in humans is encoded by the IRS2 gene. This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. Mice lacking IRS2 have a diabetic phenotype as well as a 40% reduction in brain mass. May mediate the control of various cellular processes by insulin.

Specifications

Catalog number: HA500415
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Insulin receptor substrate 2 antibody IRS 2 antibody IRS-2 antibody Irs2 antibody IRS2_HUMAN antibody
Abbreviation: Insulin receptor substrate 2 IRS-2 IRS2
Swiss Prot: Q9Y4H2 Human, P81122 Mouse,
Cellular Locus: Cytoplasm, cytosol.
Host: Rabbit
Species Reactivity: Human, Rat, Mouse
Immunogen: Recombinant protein within human aa 1-250.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: 293 cell lysate, SH-SY5Y cell lysate, A375 cell lysate, Hela cell lysate, PC-12 cell lysate, rat skeletal muscle tissue, human small intestine tissue.
Concentration: 2.07 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:600
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 137 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for IRS-2 Rabbit Polyclonal Antibody?

The catalog number for IRS-2 Rabbit Polyclonal Antibody is HA500415.

What sizes are available for IRS-2 Rabbit Polyclonal Antibody?

IRS-2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is IRS-2 Rabbit Polyclonal Antibody in stock?

IRS-2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is IRS-2 Rabbit Polyclonal Antibody used for?

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.