LRRTM1 Rabbit Polyclonal Antibody

About this product

LRRTM1 Antibody (A-2) is a high quality monoclonal LRRTM1 antibody (also designated LRRTM1 antibody) suitable for the detection of the LRRTM1 protein of mouse, rat and human origin. LRRTM1 Antibody (A-2) is available as both the non-conjugated anti-LRRTM1 antibody form, as well as multiple conjugated forms of anti-LRRTM1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The leucine-rich repeat (LRR) is a 20-30 amino acid motif that forms a hydrophobic α/β horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRRs contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRRs. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96% amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders.

Specifications

Catalog number

HA500418

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

4632401D06Rik antibody AW125451 antibody FLJ32082 antibody Leucine rich repeat transmembrane neuronal 1 antibody Leucine rich repeat transmembrane neuronal 1 protein antibody Leucine-rich repeat transmembrane neuronal protein 1 antibody LRRT1_HUMAN antibody LRRTM1 antibody Lrrtm1 leucine rich repeat transmembrane neuronal 1 antibody OTTHUMP00000194829 antibody

Abbreviation

Lrrtm1

Swiss Prot

Q86UE6 Human, Q8K377 Mouse

Cellular Locus

Cell membrane, postsynaptic cell membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within mouse LRRTM1 aa 320-360 / 522 (Extracellular).

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, FC

Positive Control

SH-SY5Y cell lysate, N2A cell lysate, rat brain tissue lysate, N2A, SH-SY5Y.

Concentration

1 mg/mL

Dilution

WB:1:500;IF-Cell:1:50-1:100;FC:1:100-1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 1% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 59 kDa.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No