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Product details

TAB3 Rabbit Polyclonal Antibody

Catalog number HA500421

Price for HA500421

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Size / count 100 µL

About this product

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Specifications

Catalog number
HA500421
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
MAP3K7IP 3 antibody Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 antibody NAP1 antibody NF-kappa-B-activating protein 1 antibody NFkB activating protein 1 antibody TAB-3 antibody Tab3 antibody TAB3_HUMAN antibody TAK1 binding protein 3 antibody TAK1-binding protein 3 antibody TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 antibody TGF-beta-activated kinase 1-binding protein 3 antibody
Abbreviation
TAB3, MAP3K7IP3
Swiss Prot
Q8N5C8 Human, Q571K4 Mouse
Cellular Locus
Cytosol, extracellular exosome, plasma membrane.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within Human TAB3 aa 513-712 / 712.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
NIH/3T3 cell lysates, human striated muscle tissue.
Concentration
1.854 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:600
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 79 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for TAB3 Rabbit Polyclonal Antibody?

The catalog number for TAB3 Rabbit Polyclonal Antibody is HA500421.

What sizes are available for TAB3 Rabbit Polyclonal Antibody?

TAB3 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is TAB3 Rabbit Polyclonal Antibody in stock?

TAB3 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is TAB3 Rabbit Polyclonal Antibody used for?

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-infla

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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