Cathepsin S Rabbit Polyclonal Antibody

Catalog number HA500422

Price for HA500422

Size / count 100 µL

About this product

Cathepsin S is a protein that in humans is encoded by the CTSS gene. Transcript variants utilizing alternative polyadenylation signals exist for this gene. Cathepsin S is a member of the peptidase C1 family of cysteine cathepsins, a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation to the MHC class II. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. Cathepsin S is a lysosomal enzyme that belongs to the papain-like protease of cysteine proteases. While a role in antigen presentation has long been recognized, it is now understood that cathepsin S has a role in itch and pain, or nociception . The nociceptive activity results from cathepsin S functioning as a signaling molecule via activation of protease-activated receptors 2 and 4 members of the G-protein coupled receptor family.

Specifications

Catalog number: HA500422
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Cathepsin S antibody CathepsinS antibody CATS_HUMAN antibody Ctss antibody
Abbreviation: CTSS
Swiss Prot: P25774 Human, O70370 Mouse, Q02765 Rat
Cellular Locus: Lysosome, Secreted, Cytoplasmic vesicle, phagosome.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Cathepsin S aa 101-331 / 331.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell
Positive Control: THP-1 cell lysate, Hela cell lysate, A431 cell lysate, PC-12 cell lysate, rat brain tissue lysate, mouse brain tissue lysate, SiHa.
Concentration: 2.305 mg/mL
Dilution: WB: 1:1,000;IF-Cell: 1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 37 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Cathepsin S Rabbit Polyclonal Antibody?

The catalog number for Cathepsin S Rabbit Polyclonal Antibody is HA500422.

What sizes are available for Cathepsin S Rabbit Polyclonal Antibody?

Cathepsin S Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Cathepsin S Rabbit Polyclonal Antibody in stock?

Cathepsin S Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cathepsin S Rabbit Polyclonal Antibody used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.