PSMC5 Rabbit Polyclonal Antibody

About this product

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

Catalog number

HA500423

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

26S protease regulatory subunit 8 antibody 26S proteasome AAA-ATPase subunit RPT6 antibody Cim3 antibody MSUG1 protein antibody p45 antibody p45/SUG antibody Proteasome 26S ATPase subunit 5 antibody Proteasome 26S subunit ATPase 5 antibody Proteasome prosome macropain 26S subunit ATPase 5 antibody Proteasome subunit p45 antibody PRS8_HUMAN antibody PSMC5 antibody Rpt6 antibody S8 antibody SUG1 antibody Tat binding protein homolog 10 antibody TBP10 antibody Thyroid hormone receptor interacting protein 1 antibody Thyroid hormone receptor-interacting protein 1 antibody Thyroid receptor interactor 1 antibody TRIP1 antibody TRIP1 (SUG1) antibody

Abbreviation

PSMC5

Swiss Prot

P62195 Human, P62196 Mouse, P62198 Rat

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human PSMC5 aa 207-406 / 406.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

A431 cell lysate, MCF-7 cell lysate, Hela cell lysate, HepG2 cell lysate, mouse testis tissue lysate, rat testis tissue lysate, rat brain tissue, human lung carcinoma tissue, A549, Hela.

Concentration

2.13 mg/mL

Dilution

WB: 1:1,000;IHC-P: 1:1,000;IF-Cell: 1:200

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 46 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No