Product details
Catalog number HA500430
Price for HA500430
Size / count 100 µL
Signal transducing adapter molecule 1 is a protein that in humans is encoded by the STAM gene. This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains an SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte growth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein.[6] STAM1 contains multiple amino acid sites that are phosphorylated and ubiquitinated.
The catalog number for STAM1 Rabbit Polyclonal Antibody is HA500430.
STAM1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.
STAM1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.
Signal transducing adapter molecule 1 is a protein that in humans is encoded by the STAM gene. This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains an SH3 domain and the immunoreceptor tyrosine-based activatio
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The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.