BCL9L Rabbit Polyclonal Antibody

Catalog number HA500459

Price for HA500459

Size / count 100 µL

About this product

Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1. In mammalian cells, BCL9 proteins contribute to, but may not be obligatory for, β-catenin–mediated transcription. BCL9L mRNA knockdown in a human colon cancer cell line induced an epithelial phenotype that was associated with the translocation of β-catenin from the nucleus to the cell membrane, suggesting that BCL9L might regulate the switch between the adhesive and transcriptional functions of β-catenin. BCL9L upregulation has been associated with breast and colon cancers, and BCL9 has recently been reported to enhance β-catenin–mediated transcription and increase the proliferation as well as the metastatic potential of tumor cells.

Specifications

Catalog number: HA500459
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: B-cell CLL antibody B-cell CLL/lymphoma 9-like protein antibody B-cell lymphoma 9-like protein antibody B9L antibody BCL9-2 antibody BCL9-like protein antibody BCL9-related beta-catenin-binding protein antibody Bcl9l antibody BCL9L_HUMAN antibody DLNB11 antibody Nuclear co factor of beta catenin signalling antibody Protein BCL9-2 antibody
Abbreviation: BCL9L, DLNB11
Swiss Prot: Q86UU0 Human, Q67FY2 Mouse,
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human BCL9L aa 351-550 / 1,499.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: Rat skin tissue, mouse skin tissue, human lung carcinoma tissue, human liver tissue, Hela cell lysate, MCF-7 cell lysate, NIH/3T3 cell lysate.
Concentration: 1.861 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 157 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for BCL9L Rabbit Polyclonal Antibody?

The catalog number for BCL9L Rabbit Polyclonal Antibody is HA500459.

What sizes are available for BCL9L Rabbit Polyclonal Antibody?

BCL9L Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is BCL9L Rabbit Polyclonal Antibody in stock?

BCL9L Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is BCL9L Rabbit Polyclonal Antibody used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.