Gli-1 Rabbit Polyclonal Antibody

Catalog number HA500465

Price for HA500465

Size / count 100 µL

About this product

Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3' . Regulates the transcription of specific genes during normal development . Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling . Plays a role in cell proliferation and differentiation via its role in SHH signaling.Tethered in the cytoplasm by binding to SUFU . Activation and translocation to the nucleus is promoted by interaction with STK36 . Phosphorylation by ULK3 may promote nuclear localization . Translocation to the nucleus is promoted by interaction with ZIC1 .Detected in testis (at protein level) . Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract. Isoform 1 is detected in brain, spleen, pancreas, liver, kidney and placenta; isoform 2 is not detectable in these tissues .

Specifications

Catalog number: HA500465
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Gli 1 antibody GLI antibody GLI family zinc finger 1 antibody GLI Kruppel family member 1 antibody gli1 antibody GLI1_HUMAN antibody Glioma associated oncogene 1 antibody Glioma associated oncogene homolog 1 (zinc finger protein) antibody Glioma associated oncogene homolog antibody Glioma-associated oncogene antibody Oncogene GLI antibody Zfp 5 antibody Zfp5 antibody Zinc finger protein GLI 1 antibody Zinc finger protein GLI1 antibody
Abbreviation: Zinc finger protein GLI1,Glioma-associated oncogene,Oncogene GLI,GLI1
Swiss Prot: P08151 Human
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within human Gli-1 aa 1-50/1106 (P08151).
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: IHC-P, IF-Cell
Positive Control: A549, LOVO, SH-SY5Y, human kidney tissue, human testis tissue.
Concentration: 1 mg/mL
Dilution: IHC-P: 1:50-1:800 ;IF-Cell: 1:50
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 118 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Gli-1 Rabbit Polyclonal Antibody?

The catalog number for Gli-1 Rabbit Polyclonal Antibody is HA500465.

What sizes are available for Gli-1 Rabbit Polyclonal Antibody?

Gli-1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Gli-1 Rabbit Polyclonal Antibody in stock?

Gli-1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Gli-1 Rabbit Polyclonal Antibody used for?

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.