CNOT1 Rabbit Polyclonal Antibody — image 1 of 2

Product details

CNOT1 Rabbit Polyclonal Antibody

Catalog number HA500466

Price for HA500466

Size / count 100 µL

About this product

Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element (ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of embryonic stem (ES) cell identity.

Specifications

Catalog number: HA500466
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: adrenal gland protein AD-005 antibody CCR4 NOT transcription complex subunit 1 isoform b antibody CCR4-associated factor 1 antibody hNOT1 antibody Negative regulator of transcription subunit 1 homolog antibody NOT1 (negative regulator of transcription 1 yeast) homolog antibody NOT1H antibody
Abbreviation: CCR4-NOT transcription complex subunit 1 CCR4-associated factor 1 Negative regulator of transcription subunit 1 homolog NOT1H hNOT1
Swiss Prot: A5YKK6 Human, G3V7M0 Rat
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Rat, Mouse
Immunogen: Recombinant protein within human CNOT1 aa 1-200 / 2376.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, FC
Positive Control: Rat brain tissue lysates, SiHa.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,1000 ;FC: 1:100-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 267/241/174 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CNOT1 Rabbit Polyclonal Antibody?

The catalog number for CNOT1 Rabbit Polyclonal Antibody is HA500466.

What sizes are available for CNOT1 Rabbit Polyclonal Antibody?

CNOT1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CNOT1 Rabbit Polyclonal Antibody in stock?

CNOT1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CNOT1 Rabbit Polyclonal Antibody used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.