ADX Rabbit Polyclonal Antibody

Catalog number HA500468

Price for HA500468

Size / count 100 µL

About this product

Adrenal ferredoxin (also adrenodoxin (ADX), adrenodoxin, mitochondrial, hepatoredoxin, ferredoxin-1 (FDX1)) is a protein that in humans is encoded by the FDX1 gene. In addition to the expressed gene at this chromosomal locus (11q22), there are pseudogenes located on chromosomes 20 and 21. Adrenodoxin is a small iron-sulfur protein that can accept and carry a single electron. Adrenodoxin functions as an electron transfer protein in the mitochondrial cytochrome P450 systems. The first enzyme in this system is adrenodoxin reductase that carries an FAD. FAD can be reduced by two electrons donated from coenzyme NADPH. These two electrons are transferred one a time to adrenodoxin. Adrenodoxin in return reduces mitochondrial cytochrome P450. This particular oxidation/reduction system is involved in the synthesis of steroid hormones in steroidogenic tissues. In addition, similar systems also function in vitamin D and bile acid synthesis in the kidney and liver respectively. Adrenodoxin has been identified in a number of different tissues but all forms have been shown to be identical and are not tissue specific.

Specifications

Catalog number: HA500468
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Adrenal ferredoxin antibody Adrenodoxin antibody Adrenodoxin, mitochondrial antibody ADX antibody ADX_HUMAN antibody FDX antibody fdx1 antibody Ferredoxin 1 antibody Ferredoxin-1 antibody Hepatoredoxin antibody LOH11CR1D antibody Mitochondrial adrenodoxin antibody mitochondrial antibody
Abbreviation: FDX1, ADX
Swiss Prot: P10109 Human, P46656 Mouse, P24483 Rat
Cellular Locus: Mitochondrion matrix.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human ADX aa 50-184.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB
Positive Control: SiHa cell lysate, SK-Br-3 cell lysate, K562 cell lysate, HepG2 cell lysate, 293T cell lysate, mouse liver tissue lysate, rat liver tissue lysate, rat testis tissue lysate.
Concentration: 1.5 mg/mL
Dilution: WB: 1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 19 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for ADX Rabbit Polyclonal Antibody?

The catalog number for ADX Rabbit Polyclonal Antibody is HA500468.

What sizes are available for ADX Rabbit Polyclonal Antibody?

ADX Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is ADX Rabbit Polyclonal Antibody in stock?

ADX Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is ADX Rabbit Polyclonal Antibody used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.