p107 Rabbit Polyclonal Antibody — image 1 of 3

Product details

p107 Rabbit Polyclonal Antibody

Catalog number HA500481

Price for HA500481

Size / count 100 µL

About this product

The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

Catalog number: HA500481
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 107 kDa retinoblastoma-associated protein antibody Cellular protein 107 antibody Cellular protein p107 antibody CP107 antibody MGC40006 antibody p107 antibody PRB1 antibody RBL1 antibody RBL1_HUMAN antibody Retinoblastoma like protein 1 antibody retinoblastoma-like 1 (p107) antibody Retinoblastoma-like protein 1 antibody
Abbreviation: RBL1
Swiss Prot: P28749 Human
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human p107 aa 869-1,068 / 1,068.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: Raji cell lysates, human colon carcinoma tissue, human placenta tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 121 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for p107 Rabbit Polyclonal Antibody?

The catalog number for p107 Rabbit Polyclonal Antibody is HA500481.

What sizes are available for p107 Rabbit Polyclonal Antibody?

p107 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is p107 Rabbit Polyclonal Antibody in stock?

p107 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is p107 Rabbit Polyclonal Antibody used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.