GSDMA Rabbit Polyclonal Antibody

Catalog number HA500498

Price for HA500498

Size / count 100 µL

About this product

May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)- bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity. The physiological relevance of these observations is unknown (Probable).

Specifications

Catalog number: HA500498
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: FKSG9 antibody Gasdermin 1 antibody Gasdermin A antibody Gasdermin-1 antibody Gasdermin-A antibody GSDM antibody GSDM1 antibody GSDMA antibody GSDMA_HUMAN antibody
Abbreviation: GSDMA
Swiss Prot: Q96QA5 Human,
Cellular Locus: Cytosol, perinuclear region; Cell membrane.
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within human GSDMA aa 1-200.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB
Positive Control: Human skin tissue lysate, rat skin tissue lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 49 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for GSDMA Rabbit Polyclonal Antibody?

The catalog number for GSDMA Rabbit Polyclonal Antibody is HA500498.

What sizes are available for GSDMA Rabbit Polyclonal Antibody?

GSDMA Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is GSDMA Rabbit Polyclonal Antibody in stock?

GSDMA Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is GSDMA Rabbit Polyclonal Antibody used for?

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

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