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Product details

CD21 Mouse Monoclonal Antibody [A4E5]

Catalog number HA600001

Price for HA600001

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Size / count 100 µL

About this product

CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigens.

Specifications

Catalog number
HA600001
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
C3DR antibody CD 21 antibody CD21 antibody Complement C3d receptor antibody Complement component (3d/Epstein Barr virus) receptor 2 antibody Complement receptor type 2 antibody CR antibody Cr2 antibody CR2_HUMAN antibody CVID7 antibody EBV receptor antibody EBV-R antibody Epstein Barr virus receptor antibody Epstein-Barr virus receptor antibody EVBR antibody SLEB9 antibody
Abbreviation
Complement receptor type 2 Cr2 Complement C3d receptor Epstein-Barr virus receptor EBV receptor CR2 CD21
Swiss Prot
P20023 Human
Cellular Locus
Cell membrane, Membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within human CD21 aa 980-1033.
Isotype
IgG2b
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Raji cell lysate, Jurkat cell lysate, human tonsil tissue, human spleen tissue, SW620, 293T.
Concentration
2 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:100-1:500
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 113 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for CD21 Mouse Monoclonal Antibody [A4E5]?

The catalog number for CD21 Mouse Monoclonal Antibody [A4E5] is HA600001.

What sizes are available for CD21 Mouse Monoclonal Antibody [A4E5]?

CD21 Mouse Monoclonal Antibody [A4E5] is available in the following size(s): 100 µL.

Is CD21 Mouse Monoclonal Antibody [A4E5] in stock?

CD21 Mouse Monoclonal Antibody [A4E5] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD21 Mouse Monoclonal Antibody [A4E5] used for?

CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B ce

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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