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Product details

MICA Mouse Monoclonal Antibody [A4C5]

Catalog number HA600002

Price for HA600002

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Size / count 100 µL

About this product

MHC class I polypeptide–related sequence A (MICA) is a highly polymorphic cell surface glycoprotein encoded by the MICA gene located within MHC locus. MICA is related to MHC class I and it has similar domain structure, however, it is not associated with β2-microglobulin nor binds peptides as conventional MHC class I molecules do. MICA rather functions as a stress-induced ligand (as a danger signal) for integral membrane protein receptor NKG2D ("natural-killer group 2, member D"). MICA is broadly recognized by NK cells, γδ T cells, and CD8+ αβ T cells which carry NKG2D receptor on their cell surface and which are activated via this interaction.

Specifications

Catalog number
HA600002
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
HLA class I antigen antibody FLJ36918 antibody FLJ60820 antibody MGC111087 antibody MGC21250 antibody MHC class I chain related gene A protein antibody MHC class I chain related protein A antibody MHC class I chain related protein A HLA B HLA C antibody MHC class I polypeptide related sequence A antibody MHC class I polypeptide-related sequence A antibody MHC class I related protein antibody MIC A antibody MIC-A antibody micA antibody MICA_HUMAN antibody OTTHUMP00000029088 antibody OTTHUMP00000044528 antibody OTTHUMP00000165170 antibody OTTHUMP00000165172 antibody PERB11.1 antibody Stress inducible class I homolog antibody
Abbreviation
MIC-A MHC class I polypeptide-related sequence A
Swiss Prot
Q29983 Human
Cellular Locus
Cell membrane, Cytoplasm, Membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human MICA aa 200-300.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB
Positive Control
MCF-7 cell lysate, Hela cell lysate.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:1,000
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 43 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for MICA Mouse Monoclonal Antibody [A4C5]?

The catalog number for MICA Mouse Monoclonal Antibody [A4C5] is HA600002.

What sizes are available for MICA Mouse Monoclonal Antibody [A4C5]?

MICA Mouse Monoclonal Antibody [A4C5] is available in the following size(s): 100 µL.

Is MICA Mouse Monoclonal Antibody [A4C5] in stock?

MICA Mouse Monoclonal Antibody [A4C5] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MICA Mouse Monoclonal Antibody [A4C5] used for?

MHC class I polypeptide–related sequence A (MICA) is a highly polymorphic cell surface glycoprotein encoded by the MICA gene located within MHC locus. MICA is related to MHC class I and it has similar domain structure, however, it is not associated with β2-microglobulin nor binds peptides as convent

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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